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Ankylosis or anchylosis (from Greek ἀγκύλος, bent, crooked) is a stiffness of a joint due to abnormal adhesion and rigidity of the bones of the joint, which may be the result of injury or disease. The rigidity may be complete or partial and may be due to inflammation of the tendinous or muscular structures outside the joint or of the tissues of the joint itself.[1]

Ankylosis
North Atlantic right whale Ankylosis Picture 0119.jpg
Osseous ankylosis has fused two vertebrae of this North Atlantic right whale specimen
Classification and external resources
Specialtyrheumatology
ICD-10M24.6
ICD-9-CM718.5
DiseasesDB29910
MeSHD000844

When the structures outside the joint are affected, the term "false ankylosis" has been used in contradistinction to "true ankylosis", in which the disease is within the joint. When inflammation has caused the joint-ends of the bones to be fused together, the ankylosis is termed osseous or complete and is an instance of synostosis. Excision of a completely ankylosed shoulder or elbow may restore free mobility and usefulness to the limb. "Ankylosis" is also used as an anatomical term, bones being said to ankylose (or anchylose) when, from being originally distinct, they coalesce, or become so joined together that no motion can take place between them.[1]

In 2014, Liliana Cernecca, a six-year-old girl at the time, was only able to open her mouth a couple millimeters after one of her jaw joints fused. She underwent surgery to correct her jaw ankylosis at King's College Hospital in London, during which her jaw was operated on and unlocked. She was said to be one of the youngest patients to have undergone this surgery.[2]

CausesEdit

X-ray of the wrist of a woman with rheumatoid arthritis, showing unaffected carpal bones in the left image, and ankylosing fusion of the carpal bones 8 years later in the right image.

Fossil recordEdit

Evidence for ankylosis found in the fossil record is studied by paleopathologists, specialists in ancient disease and injury. Ankylosis has been reported in dinosaur fossils from several species, including Allosaurus fragilis, Becklespinax altispinax, Poekilopleuron bucklandii, and Tyrannosaurus rex (including the Stan specimen).[6]

ReferencesEdit

  1. ^ a b   One or more of the preceding sentences incorporates text from a publication now in the public domainChisholm, Hugh, ed. (1911). "Ankylosis". Encyclopædia Britannica. 2 (11th ed.). Cambridge University Press. p. 58.
  2. ^ Gallagher, James (2014-02-11). "The girl whose mouth was locked shut". BBC News. Retrieved 2017-11-21.
  3. ^ "Questions and Answers about Ankylosing Spondylitis". NIAMS. June 2016. Retrieved 28 September 2016.
  4. ^ Berenbaum F (2013). "Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)". Osteoarthritis and Cartilage. 21 (1): 16–21. doi:10.1016/j.joca.2012.11.012. PMID 23194896.
  5. ^ Deeb, G. R.; Yih, WY; Merrill, RG & Lundeen, RC (1999). "Noma: report of a case resulting in bony ankylosis of the maxilla and mandible". Dentomaxillofacial Radiology. 28 (6): 378–382. doi:10.1038/sj.dmfr.4600475. PMID 10578195..
  6. ^ Molnar, R. E., 2001, Theropod paleopathology: a literature survey: In: Mesozoic Vertebrate Life, edited by Tanke, D. H., and Carpenter, K., Indiana University Press, p. 337-363.