Acapulco is a city and major sea port in the state of Guerrero on the Pacific coast of Mexico.
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Acapulco may refer to:
- Acapulco, Peru, a town in the Zorritos District of the Contralmirante Villar Province, in the Tumbes Region of Peru
- Acapulco (municipality)
- Sounine plage, a beach nicknamed 'Acapulco' adjoining the village of Sounine, Tunisia
- Acapulco Mexican Restaurant and Cantina, a restaurant chain in California and Oregon
- The local Philippines name for Senna alata (= Cassia alata)