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The 2016 Winston-Salem Open was a men's tennis tournament played on outdoor hard courts. It was the 48th edition of the Winston-Salem Open (as successor to previous tournaments in New Haven and Long Island), and part of the ATP World Tour 250 Series of the 2016 ATP World Tour. It took place at Wake Forest University in Winston-Salem, North Carolina, United States, from August 23 through August 29, 2015. It was the last event on the 2016 US Open Series before the 2016 US Open.
| 2016 Winston-Salem Open | |
|---|---|
| Date | August 21–27 |
| Edition | 48th |
| Category | ATP World Tour 250 Series |
| Draw | 48S/16D |
| Surface | Hard / outdoor |
| Location | Winston-Salem, North Carolina, USA |
| Venue | Wake Forest University |
| Champions | |
| Singles | |
 Pablo Carreño Busta | |
| Doubles | |
Guillermo García López /  Henri Kontinen | |
Singles main-draw entrants edit
Seeds edit
| Country | Player | Rank* | Seed |
|---|---|---|---|
 FRA
|
Richard Gasquet | 15 | 1 |
| ESP
|
Roberto Bautista Agut | 17 | 2 |
 URU
|
Pablo Cuevas | 19 | 3 |
 USA
|
Steve Johnson | 23 | 4 |
 RSA
|
Kevin Anderson | 24 | 5 |
| USA
|
Sam Querrey | 29 | 6 |
| FRA
|
Gilles Simon | 31 | 7 |
| ESP
|
Albert Ramos Viñolas | 33 | 8 |
 SRB
|
Viktor Troicki | 35 | 9 |
 POR
|
João Sousa | 36 | 10 |
 ITA
|
Paolo Lorenzi | 40 | 11 |
 RUS
|
Andrey Kuznetsov | 41 | 12 |
 ARG
|
Federico Delbonis | 43 | 13 |
 CYP
|
Marcos Baghdatis | 44 | 14 |
| ESP
|
Fernando Verdasco | 45 | 15 |
| ESP
|
Pablo Carreño Busta | 48 | 16 |
- Rankings are as of August 15, 2016
Other entrants edit
The following players received wildcards into the singles main draw:
The following player received entry using a protected ranking:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
Withdrawals edit
- Before the tournament
Borna Ćorić →replaced by 
Daniel Evans
Marcel Granollers →replaced by 
Víctor Estrella Burgos
Ernests Gulbis →replaced by 
Pierre-Hugues Herbert- Nicolas Mahut →replaced by
Lukáš Rosol 
Juan Mónaco →replaced by 
Evgeny Donskoy- Benoît Paire →replaced by
Damir Džumhur - Guido Pella →replaced by Stéphane Robert
Dudi Sela →replaced by 
Jan-Lennard Struff- Horacio Zeballos →replaced by
Tim van Rijthoven
- During the tournament
Retirements edit
Doubles main-draw entrants edit
Seeds edit
| Country | Player | Country | Player | Rank1 | Seed |
|---|---|---|---|---|---|
 POL
|
Łukasz Kubot | SRB
|
Nenad Zimonjić | 58 | 1 |
 CRO
|
Mate Pavić |  NZL
|
Michael Venus | 78 | 2 |
 SWE
|
Robert Lindstedt |  PAK
|
Aisam-ul-Haq Qureshi | 79 | 3 |
| USA
|
Eric Butorac | USA
|
Scott Lipsky | 86 | 4 |
- Rankings are as of August 15, 2016
Other entrants edit
The following pairs received wildcards into the doubles main draw:
Champions edit
Singles edit
- Pablo Carreño Busta def. Roberto Bautista Agut, 6–7(6–8), 7–6(7–1), 6–4
Doubles edit
- Guillermo García López /
Henri Kontinen def. Andre Begemann / 
Leander Paes, 4–6, 7–6(8–6), [10–8]