The 2000 Mexx Benelux Open was a women's tennis tournament played on outdoor clay courts in Antwerp, Belgium that was part of the Tier IV category of the 2000 WTA Tour. It was the seventh edition of the tournament and was held from 15 May until 21 May 2000. First-seeded Amanda Coetzer won the singles title and the accompanying $22,000 first-prize money.
|2000 Mexx Benelux Open|
|Date||15–21 May 2000|
|Draw||32S / 16D|
|Surface||Clay / outdoor|
|Sabine Appelmans / Kim Clijsters|
- It was Coetzer's first singles title of the year and the 7th of her career.