The 1981 Tour of the Basque Country was the 21st edition of the Tour of the Basque Country cycle race and was held from 6 April to 10 April 1981. The race started in Lazkao and finished at Iturriotz. The race was won by Silvano Contini of the Bianchi team.
|Dates||6–10 April 1981|
|Distance||812.6 km (504.9 mi)|
|Winning time||22h 07' 30"|
|Final general classification|