The 1948 United States Senate election in South Dakota took place on November 2, 1948. Incumbent Republican Senator Harlan J. Bushfield, suffering from poor health, declined to run for re-election. On September 27, 1948, he died in office; his wife, Vera C. Bushfield, was appointed to succeed him. Congressman Karl E. Mundt easily won the Republican primary and advanced to the general election, where he was opposed by Democratic nominee John A. Engel, an attorney. Hundt defeated Engel in a landslide.
1948 United States Senate election in South Dakota