1650 (MDCL) was a common year starting on Saturday of the Gregorian calendar and a common year starting on Tuesday of the Julian calendar, the 1650th year of the Common Era (CE) and Anno Domini (AD) designations, the 650th year of the 2nd millennium, the 50th year of the 17th century, and the 1st year of the 1650s decade. As of the start of 1650, the Gregorian calendar was 10 days ahead of the Julian calendar, which remained in localized use until 1923.
|Ab urbe condita||2403|
|Balinese saka calendar||1571–1572|
|English Regnal year||1 Cha. 2 – 2 Cha. 2|
|Chinese calendar||己丑年 (Earth Ox)|
4346 or 4286
— to —
庚寅年 (Metal Tiger)
4347 or 4287
|- Vikram Samvat||1706–1707|
|- Shaka Samvat||1571–1572|
|- Kali Yuga||4750–4751|
|Japanese calendar||Keian 3|
|Julian calendar||Gregorian minus 10 days|
|Minguo calendar||262 before ROC|
|Thai solar calendar||2192–2193|
1776 or 1395 or 623
— to —
1777 or 1396 or 624
|Wikimedia Commons has media related to 1650.|
- April 27 – Battle of Carbisdale: A Royalist army invades mainland Scotland from the Orkney Islands, but is defeated by a Covenanter army.
- May 17 – A quarter of the New Model Army at the Siege of Clonmel in Ireland is trapped and killed.
- June 9 – The Harvard Corporation, the more powerful of the two administrative boards of Harvard, is established (the first legal corporation in the Americas).
- June 23 – Claimant King Charles II of England, Scotland and Ireland arrives in Scotland (at Garmouth), the only one of the three kingdoms that has accepted him as ruler.
- August 13 – Colonel George Monck forms Monck's Regiment of Foot, forerunner of the Coldstream Guards.
- September 3 – Third English Civil War: Battle of Dunbar (1650) – Parliamentarian forces under Oliver Cromwell defeat a Scottish army, commanded by David Leslie.
- September 27 – The Kolumbo volcano on Santorini experiences a massive eruption (VEI 6).
- September 29 – Henry Robinson opens his Office of Addresses and Encounters, a form of employment exchange, in Threadneedle Street, London.
- November 4 – William III of Orange becomes Prince of the House of Orange at the moment of his birth, succeeding his father, who had died a few days earlier. He does not become stadtholder, so the United Provinces becomes a true republic.
- December 14 – Anne Greene is hanged at Oxford Castle in England for infanticide, having concealed an illegitimate stillbirth. The following day she revives in the dissection room and, being pardoned, lives until 1665.
- December 25 – Thomas Cooper, former Usher of Gresham's School, England, is hanged as a Royalist rebel.
- The first modern Palio di Siena horserace is held in Itlay.
- Puritans chop down the original Glastonbury Thorn in England.
- English highwayman and Captain James Hind campaigns for the Royalist cause (according to his own account).
- Jews are allowed to return to France.
- Three-wheeled wheelchairs are invented in Nuremberg by watchmaker Stephan Farffler.
- Ethiopia deports Portuguese diplomats and missionaries.
- Einkommende Zeitungen becomes the first German newspaper (ceases 1918).
- The town of Sharon, Massachusetts is founded.
- Estimation – Istanbul becomes the largest city of the world, taking the lead from Beijing.
- January 1 – George Rooke, Royal Navy admiral (d. 1709)
- January 10 – Countess Sophie Amalie of Nassau-Siegen, Duchess consort of Courland (1682-1688) (d. 1688)
- February 2 – Nell Gwyn, English actress and royal mistress (d. 1687)
- February 5 – Anne-Jules, 2nd duc de Noailles, French general (d. 1708)
- February 26 – Tomás Marín de Poveda, 1st Marquis of Cañada Hermosa, Royal Governor of Chile (d. 1703)
- February 27 – Jan Verkolje, Dutch painter (d. 1693)
- March 6 – John Conyers (MP born 1650), English politician (d. 1725)
- March 24 – Sir Jonathan Trelawny, 3rd Baronet, British bishop (d. 1721)
- March 25
- April 10 – Sebastiano Antonio Tanara, Spanish Catholic cardinal (d. 1724)
- April 15 – Hedwig of the Palatinate-Sulzbach, Archduchess of Austria, Duchess of Saxe-Lauenburg (d. 1681)
- April 18 – Sir Edward Dering, 3rd Baronet, English politician (d. 1689)
- April 20
- April 27 – Charlotte Amalie of Hesse-Kassel, Queen Consort of Denmark (1670-1699) (d. 1714)
- May 19 – Cornelis HrR Ridder de Graeff, Dutch nobleman and chief landholder of the Zijpe and Haze Polder (d. 1678)
- May 26 – John Churchill, 1st Duke of Marlborough, English general (d. 1722)
- June 5 – Ogasawara Nagashige, Japanese daimyō (d. 1732)
- June 14 – Carlo Alessandro Guidi, Italian lyric poet (d. 1712)
- June 25 – Joseph Sherman (Massachusetts Bay Colony), American politician (d. 1731)
- July 1 – Maria Anna Vasa, Polish princess (d. 1651)
- July 6 – Frederick Casimir Kettler, Duke of Courland and Semigallia (d. 1698)
- July 25 – William Burkitt, English biblical expositor, vicar in Dedham (d. 1703)
- July 30 – Edward Lewis (Devizes MP), English politician (d. 1674)
- August 7 – Louis Joseph, Duke of Guise (d. 1671)
- August 16 – Vincenzo Coronelli, Franciscan friar, Italian cartographer, encyclopedist (d. 1718)
- August 17 – Jean Gaston, Duke of Valois (d. 1652)
- August 27 – Carl Philipp, Reichsgraf von Wylich und Lottum, Prussian field marshal (d. 1719)
- August 30 – Ludovico Sabbatini, Italian priest (d. 1724)
- September 7 – Juan Manuel María de la Aurora, 8th duke of Escalona, Spanish aristocrat (d. 1725)
- September 14 – Theophilus Oglethorpe, English soldier, MP (d. 1702)
- September 20 – Adrian Beverland, Dutch philosopher and jurist who settled in England (d. 1716)
- September 23 – Jeremy Collier, English theatre critic, non-juror bishop and theologian (d. 1726)
- October 9 – René Auguste Constantin de Renneville, French writer (d. 1723)
- October 10
- October 19 – Charles Erskine, Earl of Mar (d. 1689)
- October 20 – Robert Shirley, 1st Earl Ferrers, English peer and courtier (d. 1717)
- October 21 – Jean Bart, French admiral (d. 1702)
- October 24 – Steven Blankaart, Dutch entomologist (d. 1704)
- November 4 – King William III of England, Scotland, and Ireland (d. 1702)
- November 7 – John Robinson, English diplomat (d. 1723)
- November 17 – Joanna Koerten, Dutch painter (d. 1715)
- November 18 – Robert Walpole (1650–1700), English politician (d. 1700)
- November 19 – Henry, Duke of Saxe-Römhild (d. 1710)
- November 23 – Joseph Oriol, Spanish Catholic priest, saint (d. 1702)
- November 28 – Jan Palfijn, Flemish surgeon and obstetrician (d. 1730)
- November 30 – Domenico Martinelli, Italian architect (d. 1718)
- December 3 – August of Saxe-Weissenfels (1650–1674), Prince of Saxe-Weissenfels and provost of Magdeburg (d. 1674)
- December 6 – Johann Friedrich Mayer (theologian), German Lutheran theologian (d. 1712)
- December 10 – Theophilus Hastings, 7th Earl of Huntingdon (d. 1701)
- December 16
- December 17 – Christoph Arnold, German astronomer (d. 1695)
- December 25 – Claude Aveneau, French missionary (d. 1711)
- date unknown
- January 7 – Louis I, Prince of Anhalt-Köthen, German prince (b. 1579)
- January 18 – Matteo Rosselli, Italian painter (b. 1578)
- January 23 – Philip Herbert, 4th Earl of Pembroke (b. 1584)
- February 11
- February 26 – Claude Favre de Vaugelas, Savoyard grammarian and man of letters (b. 1585)
- March 8 – Antonio Tornielli, Italian Catholic prelate (b. 1579)
- March 11 – John Henderson, 5th of Fordell, Scottish noble (b. 1605)
- March 16 – Sophie Elisabeth of Brandenburg, Duchess consort of Saxe-Altenburg (b. 1616)
- March 25
- Elisabeth of Brunswick-Wolfenbüttel, Duchess of Saxe-Altenburg (b. 1593)
- John Williams, Welsh clergyman and political advisor to King James I (b. 1582)
- April 3 – Christian Gueintz, German teacher and writer-grammarian (b. 1592)
- April 18 – Simonds d'Ewes, English antiquarian and politician (b. 1602)
- April 21 – Yagyū Jūbei Mitsuyoshi, Japanese samurai (b. 1607)
- April 22 – Stephanius, Danish historian (b. 1599)
- May 7 – Kanō Naonobu, Japanese painter of the Kanō school of painting (b. 1607)
- May 21 – James Graham, 1st Marquess of Montrose, Scottish royalist (b. 1612)
- May 20 – Francesco Sacrati, Italian composer (b. 1605)
- May 25 – Michel Particelli d'Emery, French politician (b. 1596)
- May 28 – Agnes of Hesse-Kassel, Princess consort of Anhalt-Dessau (b. 1606)
- June 8 – Maximilian von und zu Trauttmansdorff, Austrian diplomat (b. 1584)
- June 18 – Christoph Scheiner, German astronomer (b. 1573 or 1575)
- June 19
- June 26 – Hedwig of Brunswick-Wolfenbüttel, Duchess consort of Pomerania (b. 1595)
- June 28 – Jean Rotrou, French poet and tragedian (b. 1609)
- June 30 – Niccolò Cabeo, Italian Jesuit writer, theologian (b. 1586)
- July 2 – Marion Delorme, French courtesan known for her relationships with the important men of her time (b. 1613)
- July 16 – Margaretha van Valckenburch, Dutch shipowner, only female member of the VOC (b. 1565)
- July 18 – Robert Levinz, English Royalist, hanged in London by Parliamentary forces as a spy (b. 1615)
- August – John Parkinson, English herbalist and botanist (b. 1567)
- August 16 – Cesare Monti, Italian cardinal, Archbishop of Milan (b. 1593)
- September 7 – Scévole de Sainte-Marthe, French historian (b. 1571)
- September 8 – Elizabeth Stuart, second daughter of King Charles I of England (b. 1635)
- September 13 – Ferdinand of Bavaria (b. 1577)
- September 14 – Josias von Rantzau, Marshal of France (b. 1609)
- September 24 – Charles de Valois, Duke of Angoulême, son of Charles IX of France (b. 1573)
- October 25 – Franciscus Quaresmius, Italian writer and orientalist (b. 1583)
- October 29 – David Calderwood, Scottish historian (b. 1575)
- November 6 – William II, Prince of Orange (b. 1626)
- November 24 – Manuel Cardoso, Portuguese composer (b. 1566)
- December 13 – (bapt.) Phineas Fletcher, English poet (b. 1582)
- December 31 – Dorgon, Manchu prince (b. 1612)
- date unknown – Catalina de Erauso, Spanish-Mexican nun and soldier (b. 1592)
- A Scholler in Oxford (1651). Newes from the Dead, or a True and Exact Narration of the Miraculous Deliverance of Anne Greene; whereunto are prefixed certain Poems casually written upon that subject. Oxford: printed by Leonard Lichfield for Tho. Robinson. Includes Latin verses by Christopher Wren.
- Hughes, J. Trevor (1982). "Miraculous Deliverance of Anne Green: An Oxford Case Of Resuscitation In The Seventeenth Century". British Medical Journal. 285 (6357): 1792–1793. doi:10.1136/bmj.285.6357.1792. JSTOR 29509089. PMC 1500297. PMID 6816370. Retrieved October 27, 2014.
- Bradley, Emily Tennyson (1893). "Levinz, Robert". In Lee, Sidney (ed.). Dictionary of National Biography. 33. London: Smith, Elder & Co. p. 161.