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|Ab urbe condita||2226|
|Balinese saka calendar||1394–1395|
|English Regnal year||12 Edw. 4 – 13 Edw. 4|
|Chinese calendar||壬辰年 (Water Dragon)|
4169 or 4109
— to —
癸巳年 (Water Snake)
4170 or 4110
|- Vikram Samvat||1529–1530|
|- Shaka Samvat||1394–1395|
|- Kali Yuga||4573–4574|
|Japanese calendar||Bunmei 5|
|Minguo calendar||439 before ROC|
|Thai solar calendar||2015–2016|
1599 or 1218 or 446
— to —
1600 or 1219 or 447
|Wikimedia Commons has media related to 1473.|
- February 12 – The first complete printed edition of Avicenna's The Canon of Medicine (Latin translation) is published in Milan.
- August 11 – Battle of Otlukbeli: Ottoman Sultan Mehmed II defeats the White Sheep Turkmens, led by Uzun Hasan.
- Axayacatl, Aztec ruler of Tenochtitlan, invades the territory of the neighboring Aztec city of Tlatelolco. The ruler of Tlatelolco is killed, and replaced by a military governor; Tlatelolco loses its independence.
- Possible discovery of Bacalao (possibly Newfoundland, North America) by Didrik Pining and João Vaz Corte-Real.
- The Almanach cracoviense ad annum 1474 is published in Poland.
- The city walls and defensive moat are built in Celje, Slovenia.
- Marsilio Ficino becomes a Catholic priest.
- Recuyell of the Historyes of Troye is the first book to be printed in English, by William Caxton.
- Stephen the Great of Moldavia refuses to pay tribute to the Ottomans. This will attract an Ottoman invasion resulting in 1475 in the greatest defeat of the Ottomans so far.
- February 19 – Nicolaus Copernicus, Polish astronomer and mathematician (d. 1543)
- February 25 – Al-Mutawakkil Yahya Sharaf ad-Din, Imam of the Zaidi state in Yemen (d. 1555)
- March 3 – Asakura Sadakage, 9th head of the Asakura clan (d. 1512)
- March 14 – Reinhard IV, Count of Hanau-Münzenberg (1500–1512) (d. 1512)
- March 16 – Henry IV, Duke of Saxony (1539–1541) (d. 1541)
- March 17 – King James IV of Scotland, King of Scots from 11 June 1488 to his death (d. 1513)
- April 2 – John Corvinus, Hungarian noble (d. 1504)
- July 4 – Matilda of Hesse, German noblewoman (d. 1505)
- July 6 – James III of Cyprus, son of James II of Cyprus and Catherine Cornaro, king of Cyprus (d. 1474)
- July – Maddalena de' Medici, Italian noble (d. 1528)
- August 14 – Margaret Pole, 8th Countess of Salisbury (d. 1541)
- August 17 – Richard, Duke of York, one of the Princes in the Tower (d. 1483)
- August 25 – Margaret of Münsterberg, Duchess consort and regent of Anhalt (d. 1530)
- September 2 – Ercole Strozzi, Italian poet (d. 1508)
- September 23 – Thomas Lovett III, High Sheriff of Northamptonshire (d. 1542)
- September 24 – Georg von Frundsberg, German knight and landowner (d. 1528)
- October 26 – Friedrich of Saxony, Grand Master of the Teutonic Knights (d. 1510)
- date unknown – Thomas Howard, 3rd Duke of Norfolk, English Tudor politician (d. 1555)
- January 24 – Conrad Paumann, German composer (b. c. 1410)
- February 23 – Arnold, Duke of Guelders (b. 1410)
- April 3 – Alessandro Sforza, Italian condottiero (b. 1409)
- April 15 – Yamana Sōzen, Japanese daimyō and monk (b. 1404)
- May 8 – John Stafford, 1st Earl of Wiltshire, English politician (b. 1420)
- June 6 – Hosokawa Katsumoto, Japanese nobleman (b. 1430)
- June 28 – John Talbot, 3rd Earl of Shrewsbury, English Earl (b. 1448)
- July 10 – James II of Cyprus (b. c. 1440)
- November 26 – Diego Fernández de la Cueva, 1st Viscount of Huelma
- October – Contessina de' Bardi, politically active Florentine woman (b. 1390)
- December 24 – John Cantius, Polish scholar and theologian (b. 1390)
- date unknown
- probable – Patriarch Gennadios II of Constantinople (b. c. 1400)