Ethylenediamine dihydroiodide

Ethylenediamine dihydroiodide (EDDI) is a water-soluble salt derived from ethylenediamine and hydroiodic acid. It is a colorless to light yellow crystalline powder. The salt consists of the ethylenediammonium dication C2H4(NH3)22+ and iodide anions.

Ethylenediamine dihydroiodide
Names
IUPAC name
Ethane-1,2-diamine dihydroiodide
Other names
Ethylenediammonium diiodide
Ethane-1,2-diammonium iodide
Jodethamine
Hydrodine
Identifiers
3D model (JSmol)
Abbreviations EDDI
ChemSpider
ECHA InfoCard 100.024.715 Edit this at Wikidata
UNII
  • InChI=1S/C2H8N2.2HI/c3-1-2-4;;/h1-4H2;2*1H checkY
    Key: IWNWLPUNKAYUAW-UHFFFAOYSA-N checkY
  • InChI=1/C2H8N2.2HI/c3-1-2-4;;/h1-4H2;2*1H
    Key: IWNWLPUNKAYUAW-UHFFFAOYAJ
  • NCCN.I.I
  • I.I.NCCN
Properties
C2H10I2N2
Molar mass 315.92 g/mol
Appearance Colorless to light yellow crystalline powder
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Application

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EDDI is used as an additive in pet food and cattle feed with high bioavailability. Used to prevent iodine deficiency, this salt is one of the major uses of the element iodine.[1] The United States Food and Drug Administration suggests a limit of intake to 50 mg/head/day.[2] Although EDDI is generally recognized as safe (GRAS) only as a nutrient source of iodine, administration of EDDI also has preventative effects on foot rot in cattle.[3]

Other iodine supplements for animal feed include calcium iodate (most stable) and potassium iodide.

See also

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Calcium iodates are another source of nutritional iodide.

References

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  1. ^ Lyday, Phyllis A. "Iodine and Iodine Compounds" in Ullmann's Encyclopedia of Industrial Chemistry, 2005, Wiley-VCH, Weinheim, ISBN 978-3-527-30673-2 doi:10.1002/14356007.a14_381 Vol. A14 pp. 382–390.
  2. ^ The Elimination of Iodine Deficiency Disorders, A Resource Package for Central and Eastern Europe, the Commonwealth of Independent States and Baltic States
  3. ^ Berg JN, Maas JP, Paterson JA, Krause GF, Davis LE (1984). "Efficacy of ethylenediamine dihydriodide as an agent to prevent experimentally induced bovine foot rot". Am. J. Vet. Res. 45 (6): 1073–8. PMID 6146277.