What's Up, Doc?
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What's Up, Doc? may refer to:
- "What's up, doc?", a catchphrase of the cartoon character Bugs Bunny
- What's Up, Doc? (1950 film), an animated cartoon short featuring Bugs Bunny
- "What's Up, Doc?", an instrumental theme composed by Carl Stalling and used in several Bugs Bunny cartoons (later given lyrics for the 1950 animated short)
- What's Up, Doc? (1972 film), a comedy film starring Barbra Streisand and Ryan O'Neal
- What's Up Doc? (TV series), a UK Saturday morning variety series
- "Whats Up, Doc?" (Cheers), an episode of the television series Cheers
- "What's Up Doc? (Can We Rock)," a song by rap group Fu-Schnickens featuring Shaquille O'Neal
- "What's Up, Doc," an episode of the television series M*A*S*H (season 6)
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