USS Prometheus may refer to the follow ships of the United States Navy:
- USS Prometheus (1814), a brig in the United States Navy from 1814 to 1818
- USS Prometheus (AR-3), a repair ship that served during World War I and World War II
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.