Three ships in the United States Navy have been named USS Galena. They were named for various communities that, in turn, were named for a native lead sulfide, the chief ore of lead. Cities, towns, and villages with the name exist in Kansas, Illinois, Maryland, Missouri, Ohio, and Alaska.
- USS Galena (1862), was a steamship during the American Civil War.
- USS Galena (1880), a steamship, was commissioned in 1880 and decommissioned in 1890.
- USS Galena (PC-1136), a patrol boat, was commissioned in 1943 and decommissioned in 1946.
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.