Secretariat Building may refer to:
- Secretariat Building, Chandigarh in India
- Secretariat Building, New Delhi in India
- Secretariat Building, Bandar Seri Begawan in Brunei
- The United Nations Secretariat Building in Manhattan
- Former name of General Treasury Building, Sri Lanka
- Former name of Ministers' Building, Burma
- Kerala Government Secretariat, the secretariat building of the State Government of Kerala
- Malacca State Secretariat Building
- Mantralaya, Mumbai the secretariat building of the State Government of Maharashtra
- Namakkal Kavignar Maligai the secretariat building of the State Government of Tamil Nadu
- Negeri Sembilan State Secretariat Building
- Patna Secretariat the secretariat building of the State Government of Bihar
- Perlis State Secretariat Building
- Sultan Ibrahim Building, former state secretariat building of Johor
- Writers' Building, the secretariat building of the State Government of West Bengal
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