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Template:PBB/1268
Cannabinoid receptor 1 (brain)
Rendering of CNR1 from
PDB
1LVQ
Available structures
PDB
Ortholog search:
PDBe
,
RCSB
List of PDB id codes
1LVQ
,
1LVR
,
2B0Y
,
2KOE
Identifiers
Symbols
CNR1
; CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR
External IDs
OMIM
:
114610
MGI
:
104615
HomoloGene
:
7273
IUPHAR
:
CB
1
ChEMBL
:
218
GeneCards
:
CNR1 Gene
Gene Ontology
Molecular function
•
cannabinoid receptor activity
•
drug binding
Cellular component
•
plasma membrane
•
integral to plasma membrane
Biological process
•
positive regulation of acute inflammatory response to antigenic stimulus
•
response to stress
•
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
•
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
•
spermatogenesis
•
aging
•
response to nutrient
•
behavior
•
memory
•
positive regulation of neuron projection development
•
sensory perception of pain
•
positive regulation of fever generation
•
negative regulation of fatty acid beta-oxidation
•
regulation of synaptic transmission, GABAergic
•
response to lipopolysaccharide
•
negative regulation of mast cell activation
•
negative regulation of dopamine secretion
•
response to nicotine
•
response to cocaine
•
positive regulation of apoptotic process
•
response to morphine
•
response to ethanol
•
negative regulation of action potential
•
negative regulation of blood pressure
•
positive regulation of blood pressure
•
regulation of insulin secretion
•
negative regulation of nitric-oxide synthase activity
•
regulation of synaptic transmission, glutamatergic
•
maternal process involved in female pregnancy
•
regulation of feeding behavior
•
regulation of penile erection
Sources:
Amigo
/
QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species
Human
Mouse
Entrez
1268
12801
Ensembl
ENSG00000118432
ENSMUSG00000044288
UniProt
P21554
P47746
RefSeq (mRNA)
NM_001160226
NM_007726
RefSeq (protein)
NP_001153698
NP_031752
Location (UCSC)
Chr 6:
88.85 – 88.88 Mb
Chr 4:
33.92 – 33.95 Mb
PubMed
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Last modified on 9 May 2013, at 15:38