Template:Bleeding worksheet
| Condition | Prothrombin time | Partial thromboplastin time | Bleeding time | Platelet count |
|---|---|---|---|---|
| Vitamin K deficiency or warfarin | Prolonged | Normal or mildly prolonged | Unaffected | Unaffected |
| Disseminated intravascular coagulation | Prolonged | Prolonged | Prolonged | Decreased |
| Von Willebrand disease | Unaffected | Prolonged | Prolonged | Unaffected |
| Hemophilia | Unaffected | Prolonged | Unaffected | Unaffected |
| Aspirin | Unaffected | Unaffected | Prolonged | Unaffected |
| Thrombocytopenia | Unaffected | Unaffected | Prolonged | Decreased |
| Liver failure, early | Prolonged | Unaffected | Unaffected | Unaffected |
| Liver failure, end-stage | Prolonged | Prolonged | Prolonged | Decreased |
| Uremia | Unaffected | Unaffected | Prolonged | Unaffected |
| Congenital afibrinogenemia | Prolonged | Prolonged | Prolonged | Unaffected |
| Factor V deficiency | Prolonged | Prolonged | Unaffected | Unaffected |
| Factor X deficiency as seen in amyloid purpura | Prolonged | Prolonged | Unaffected | Unaffected |
| Glanzmann's thrombasthenia | Unaffected | Unaffected | Prolonged | Unaffected |
| Bernard-Soulier syndrome | Unaffected | Unaffected | Prolonged | Decreased or unaffected |
| Factor XII deficiency | Unaffected | Prolonged | Unaffected | Unaffected |
| C1INH deficiency | Unaffected | Shortened | Unaffected | Unaffected |
Notes
Platelet count in Bernard-Soulier syndrome
| Source | Quote from source |
|---|---|
| Hillman[1] | normal to slightly reduced platelet count (page 389) |
| McPhee[2] | moderate thrombocytopenia (page 530) |
| Hoffbrand[3] | variable degree of thrombocytopenia (page 341) |
| Kaplan[4] | "unaffected" (as reported by WP editor Jabway, citing page 254) |
| Lanza[5] | low platelet counts |
References
- ^ Hillman RS, Ault KA, Leporrier M, Rinder HM. (2011; edition 5.) Hematology in Clinical Practice. McGraw-Hill. ISBN 978-0-07-162699-6.
- ^ McPhee SJ, Papadakis M. (2012; edition 51.) Current Medical Diagnosis & Treatment. McGraw-Hill. ISBN 978-0-07-176372-1.
- ^ Hoffbrand AV, Moss PAH (2011). Essential Haematology.(edition 6). Wiley-Blackwell. ISBN 978-1-4051-9890-5.
- ^ Kaplan QBook - USMLE Step 1 October 4, 2011 5th edition ISBN 978-1609782245
- ^ Lanza F (2006). "Bernard-Soulier syndrome (hemorrhagiparous thrombocytic dystrophy)". Orphanet J Rare Dis. 16 (1): 46. doi:10.1186/1750-1172-1-46. PMC 1660532. PMID 17109744.
