SME

SME may stand for:

• Subject-matter expert, a person who is an expert in a particular area or topic
• Shawnee Mission East High School, a public high school in Kansas
• Small and medium enterprises, a synonym for Small and Medium-sized Business(es) (SMB)
• Standard-Model Extension, general framework for studying the violation of Lorentz and CPT symmetry in field theory
• Structure mapping engine, analogy-based AI technology by Ken Forbus based on Dedre Gentner's structure-mapping theory
• Social market economy, an economic model used in Europe / West Germany
• Soy methyl ester, biodiesel created from soybean oil
• Sevomethyl ether, USP Sevoflurane Related Compound B
• SME Server, a Linux firewall/server distribution
• Socialist market economy, an economic system of the People's Republic of China
• SME (newspaper), Slovak daily newspapers
• SME Limited, a British maker of audio pick-up arms (tonearms) and turntables
• Society of Manufacturing Engineers, a professional membership organization for engineers
• Sony Music Entertainment, a record label
• S.M. Entertainment, a Korean record label
• Spontaneous Music Ensemble
• Sloppy Meateaters, a former band from Rome, Georgia, United States
• Solar Mesosphere Explorer, a NASA artificial satellite in orbit 1981–89
• Method engineering#Situational method engineering
• SIGNAL Meta under Eclipse, an EMF-based metamodel of the SIGNAL programming language
• Surface-mount equipment, machines for the assembly of surface-mount technology electronic components