South Carolina Highway 69 may refer to:
- South Carolina Highway 69 (1930s), a former state highway from Orangeburg to Cameron
- South Carolina Highway 69 (1939–1947), a former state highway from southwest of Pelion to Swansea
- South Carolina Highway 69 (1977–1981), a former state highway from Atlantic Beach to Cherry Grove Beach
This disambiguation page lists articles about roads and streets with the same name.
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