Rothbury may refer to:
- Rothbury, New South Wales, a small town in the City of Cessnock
- Rothbury, a town and civil parish in the County of Northumberland
- United States
- Rothbury, Michigan, a village in Oceana County
- Rothbury Festival, a four-day music festival held in 2008 and 2009 in Rothbury, Michigan
- Rothbury Riot, an incident that occurred in 1929 at Rothbury, New South Wales
- Rothbury Terrier, a breed of dog also known as the Bedlington Terrier
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