Richard Olding Hynes FRS (born 29 November 1944) is a British biologist, a Howard Hughes Medical Institute Investigator,[4] and the Daniel K. Ludwig Professor for Cancer Research at the Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT).[5] His research focuses on cell adhesion and the interactions between cells and the extracellular matrix, with a particular interest in understanding molecular mechanisms of cancer metastasis.[5] He is well known as a co-discoverer of fibronectin molecules, a discovery that has been listed by Thomson Scientific ScienceWatch as a Nobel Prize candidate.[6]

Richard Hynes

Born
Richard Olding Hynes[1]

(1944-11-29) 29 November 1944 (age 79)[3]
CitizenshipAmerican
British[2]
EducationUniversity of Cambridge (BA, MA)
Massachusetts Institute of Technology (PhD)
Known forCell adhesion research
Discovery of fibronectin
AwardsCanada Gairdner International Award
E.B. Wilson Medal
Robert J. and Claire Pasarow Foundation Medical Research Award
Albert Lasker Award for Basic Medical Research
Scientific career
FieldsCell biology
InstitutionsMassachusetts Institute of Technology
Howard Hughes Medical Institute
Broad Institute
ThesisRegulation of gene expression during early cleavage in sea urchin embryos (1971)
Doctoral advisorPaul R. Gross
Doctoral studentsDenisa Wagner

Education edit

Hynes earned his B.A. in 1966 and M.A. in 1970 from the University of Cambridge, both in biochemistry. He received his Ph.D. in biology from the Massachusetts Institute of Technology in 1971. He worked as a postdoctoral fellow at the Imperial Cancer Research Fund from 1971 to 1974.[4][5][7]

Academic career edit

Hynes became a faculty member in the biology department at MIT in 1973 and was promoted to full professor in 1983. He was awarded Howard Hughes Medical Institute Investigator status in 1988. He served as the head of the biology department from 1989 to 1991 and as the director of the MIT Center for Cancer Research from 1991 to 2001, and became the Daniel K. Ludwig Professor for Cancer Research and affiliated with the Koch Institute for Integrative Cancer Research in 1999. Since 2004 he has been an associate member of the Broad Institute.[7][8]

Hynes served as the president of the American Society for Cell Biology in 2000.[7] He has been a member of the Board of Governors of the Wellcome Trust since 2007.[9] He also served on the Life Sciences jury for the Infosys Prize in 2012.

He has also published on public policy and participated in the development of United States research guidelines for stem cell research, particularly embryonic stem cells.[10]

Awards and honours edit

References edit

  1. ^ a b "Richard Olding Hynes". American Academy of Arts & Sciences. Archived from the original on 7 April 2023. Retrieved 7 April 2023.
  2. ^ a b "IOM elects Hynes". Massachusetts Institute of Technology. 25 October 1995. Archived from the original on 7 April 2023. Retrieved 7 April 2023.
  3. ^ "Hynes, Prof. Richard Olding". Who's Who 2023. Oxford University Press. 1 December 2021. Retrieved 7 April 2023.
  4. ^ a b "Richard O. Hynes, PhD". Howard Hughes Medical Institute. Retrieved 7 July 2015.
  5. ^ a b c "Richard O. Hynes". The Koch Institute. Retrieved 7 July 2015.
  6. ^ Cowin, Pamela (2013). "Leaders in Cell Adhesion: An Interview with Richard Hynes, Pioneer of Cell–Matrix Interactions". Cell Communication & Adhesion. 20 (6): 139–146. doi:10.3109/15419061.2013.857662. PMID 24274118.
  7. ^ a b c d "RICHARD O. HYNES, PhD, FRS" (PDF). Massachusetts Institute of Technology. Archived from the original (PDF) on 7 April 2023. Retrieved 7 April 2023.
  8. ^ "Richard O. Hynes". MIT Biology. Retrieved 7 July 2015.
  9. ^ "Professor Richard Hynes FRS". Wellcome Trust. Archived from the original on 8 July 2015. Retrieved 7 July 2015.
  10. ^ "Public Policy on Stem Cells". Hynes Lab. Massachusetts Institute of Technology. Retrieved 7 July 2015.
  11. ^ "Richard O. Hynes". John Simon Guggenheim Memorial Foundation. Archived from the original on 11 April 2023. Retrieved 11 April 2023.
  12. ^ "Richard Hynes". Royal Society. Archived from the original on 11 April 2023. Retrieved 11 April 2023.
  13. ^ "Richard O. Hynes, Ph.D., FRS". National Academy of Medicine. Retrieved 15 April 2023.
  14. ^ "Richard O. Hynes". National Academy of Sciences. Retrieved 15 April 2023.
  15. ^ "Richard O. Hynes". Gairdner Foundation. Archived from the original on 21 October 2021. Retrieved 21 October 2021.
  16. ^ "E.B. Wilson Medal". American Society for Cell Biology. Archived from the original on 17 August 2015. Retrieved 4 July 2015.
  17. ^ a b "Richard O. Hynes, PhD". American Association for Cancer Research. Archived from the original on 10 April 2023. Retrieved 15 April 2023.
  18. ^ "Richard Hynes". American Society for Cell Biology. Retrieved 15 April 2023.
  19. ^ "An Interview with Richard Hynes David Rall Medal 2017". National Academy of Medicine. Retrieved 15 April 2023.
  20. ^ "2022 Albert Lasker Basic Medical Research Award". Lasker Foundation. Retrieved 15 April 2023.