Phenylpiracetam

Phenotropil

Systematic (IUPAC) name
(RS)-2-(2-oxo-4-phenylpyrrolidin-1-yl)acetamide
Clinical data
Pregnancy cat.	Unknown
Legal status	Legal
Routes	Oral
Pharmacokinetic data
Bioavailability	~100 %
Metabolism	None
Half-life	3-5 hours
Excretion	Urine ~40% bile and perspiration ~60%
Identifiers
CAS number	77472-70-9 Y
ATC code	None
PubChem	CID 132441
ChemSpider	116950
Chemical data
Formula	C12H14N2O2
Mol. mass	218.3 g/mol
SMILES C1=CC=CC=C1C2CN(C(C2)=O)CC(=O)N
InChI InChI=1S/C12H14N2O2/c13-11(15)8-14-7-10(6-12(14)16)9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H2,13,15) Key:LYONXVJRBWWGQO-UHFFFAOYSA-N
Y (what is this?)  (verify)

Phenylpiracetam (Phenotropil, Carphedon) is a derivative of the nootropic drug piracetam. Used as a nootropic drug that can be up to 30-60 times more potent than piracetam.^{[citation needed]} It was developed in Russia, and a small number of low-scale clinical studies have shown possible links between prescription of phenylpiracetam and improvement in a number of encephalopathic conditions, including lesions of cerebral blood pathways, and certain types of glioma.^{[citation needed]}

Medical usage

While not widely available in the West, in Russia it is available as a prescription medicine under the name Phenotropil. Packets of ten 100 mg pills are available for roughly 500 rubles (2013 price), or about $17 USD. It is typically prescribed as a general stimulant or to increase tolerance to cold and stress.^{[citation needed]}

Doping

It is also claimed to increase physical stamina and provide improved tolerance to cold. As a result, it appears on the lists of banned substances issued by the World Anti-Doping Agency. This list is applicable in all Olympic sports.

Athletes disqualified for phenotropil usage

Phenotropil 100 mg from Russia

Russian biathlon Olympic silver medalist Olga Pyleva in the 2006 Winter Olympics was disqualified from attending further events following a positive drug test. She was subsequently banned from competition for two years. It may be noteworthy that Pyleva claims that phenylpiracetam was an unlisted ingredient of a Russian medication she was prescribed by her personal doctor (not a team doctor).^{[citation needed]}

In August 2008, Russian steeplechase runner Roman Usov was pulled out of the Beijing Olympics for what media reported was a possible positive test for phenylpiracetam.

See also

• Ampakines
• Doping in sport
• Nootropic
• Piracetam
• Psychostimulants
• Racetams