Peroxisomal membrane protein PEX13 is a protein that in humans is encoded by the PEX13 gene.[4][5] It located on chromosome 2 next to KIAA1841

PEX13
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPEX13, NALD, PBD11A, PBD11B, ZWS, peroxisomal biogenesis factor 13
External IDsOMIM: 601789 MGI: 1919379 HomoloGene: 1967 GeneCards: PEX13
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002618

NM_023651

RefSeq (protein)

NP_002609

NP_076140

Location (UCSC)Chr 2: 61.02 – 61.05 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions edit

PEX13 has been shown to interact with PEX14,[6] PEX5[6][7] and PEX19.[8][9]

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162928 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Björkman J, Stetten G, Moore CS, Gould SJ, Crane DI (December 1998). "Genomic structure of PEX13, a candidate peroxisome biogenesis disorder gene". Genomics. 54 (3): 521–8. doi:10.1006/geno.1998.5520. PMID 9878256.
  5. ^ "Entrez Gene: PEX13 peroxisome biogenesis factor 13".
  6. ^ a b Otera H, Setoguchi K, Hamasaki M, Kumashiro T, Shimizu N, Fujiki Y (March 2002). "Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import". Molecular and Cellular Biology. 22 (6): 1639–55. doi:10.1128/MCB.22.6.1639-1655.2002. PMC 135613. PMID 11865044.
  7. ^ Gould SJ, Kalish JE, Morrell JC, Bjorkman J, Urquhart AJ, Crane DI (October 1996). "Pex13p is an SH3 protein of the peroxisome membrane and a docking factor for the predominantly cytoplasmic PTs1 receptor". The Journal of Cell Biology. 135 (1): 85–95. doi:10.1083/jcb.135.1.85. PMC 2121023. PMID 8858165.
  8. ^ Sacksteder KA, Jones JM, South ST, Li X, Liu Y, Gould SJ (March 2000). "PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis". The Journal of Cell Biology. 148 (5): 931–44. doi:10.1083/jcb.148.5.931. PMC 2174547. PMID 10704444.
  9. ^ Fransen M, Wylin T, Brees C, Mannaerts GP, Van Veldhoven PP (July 2001). "Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences". Molecular and Cellular Biology. 21 (13): 4413–24. doi:10.1128/MCB.21.13.4413-4424.2001. PMC 87101. PMID 11390669.

Further reading edit

External links edit