Oxomemazine

Oxomemazine
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	R06AD08 (WHO) ;
Legal status
Legal status	US: Not approved; In general: ℞ (Prescription only);
Identifiers
	IUPAC name 3-(5,5-Dioxido-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine;
CAS Number	3689-50-7 ;
PubChem CID	19396;
ChemSpider	18281 ;
UNII	305MB38V1C;
KEGG	D07401 ;
ChEMBL	ChEMBL2104734 ;
CompTox Dashboard (EPA)	DTXSID5023405 ;
ECHA InfoCard	100.020.906
Chemical and physical data
Formula	C18H22N2O2S
Molar mass	330.45 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=S3(=O)c1ccccc1N(c2c3cccc2)CC(C)CN(C)C;
	InChI InChI=1S/C18H22N2O2S/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)23(21,22)18-11-7-5-9-16(18)20/h4-11,14H,12-13H2,1-3H3 ; Key:QTQPVLDZQVPLGV-UHFFFAOYSA-N ;
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Oxomemazine is an antihistamine and anticholinergic of the phenothiazine chemical class for the treatment of cough.^[1]^[2]

References edit

^ Pujet JC, Keddad K, Sévenier F, Jolivet-Landreau I (2002). "[Comparative study of two antitussive drugs in the treatment of acute dry cough of infectious origin (prospective, randomized, single blind study)]". Therapie. 57 (5): 457–63. PMID 12611200.
^ Lee SW, Woo CW, Kim JG (December 1994). "Selectivity of oxomemazine for the M1 muscarinic receptors". Archives of Pharmacal Research. 17 (6): 443–51. doi:10.1007/BF02979123. PMID 10319156. S2CID 34007107.

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