neXtProt is an on-line knowledge platform on human proteins. It strives to be a comprehensive resource that provides a variety of types of information on human proteins, such as their function, subcellular location, expression, interactions and role in diseases. The major part of the information in neXtProt [2] is obtained from the UniProt Swiss-Prot database but it is complemented by data originating from high-throughput studies with an emphasis on proteomics. neXtProt offers also an advanced search capacity based on the SPARQL technology as well as an API that allows to programmatically extract the data stored in the resource. It is developed by the CALIPHO group[3] directed by Amos Bairoch and Lydie Lane of the Swiss Institute of Bioinformatics (SIB).

neXtProt
Content
DescriptionneXtProt: exploring the universe of human proteins
Data types
captured
Protein annotation
OrganismsHuman
Contact
Research centerSwiss Institute of Bioinformatics
LaboratoryCALIPHO
Primary citationGaudet, et al. (2016)[1]
Access
Websitewww.nextprot.org
Tools
WebSearch, BLAST, SNORQL
Miscellaneous
LicenseCreative Commons Attribution 4.0
VersioningYes
Data release
frequency
Data: 3 times per year
Curation policyYes - manual and automatic
Bookmarkable
entities
Yes - individual protein entries views and searches

References edit

  1. ^ Gaudet, P; Michel, PA; Zahn-Zabal, M; Britan, A; Cusin, I; Domagalski, M; Duek, PD; Gateau, A; Gleizes, A; Hinard, V; de Laval, VR; Lin, J; Nikitin, F; Schaeffer, M; Teixeira, D; Lane, L; Bairoch, A (29 November 2016). "The neXtProt knowledgebase on human proteins: 2017 update". Nucleic Acids Research. 45 (D1): D177–D182. doi:10.1093/nar/gkw1062. PMC 5210547. PMID 27899619.
  2. ^ Lane Lydie (2012). "neXtProt: a knowledge platform for human proteins". Nucleic Acids Research. 40 (Database issue): D76–D83. doi:10.1093/nar/gkr1179. PMC 3245017. PMID 22139911.
  3. ^ CALIPHO group, on the web site of the SIB

External links edit