Napoca can refer to:
- Cluj-Napoca, a major city in Transylvania, Romania.
- Napoca (ancient city), an ancient Roman settlement in Dacia, known today as Cluj-Napoca.
- Napoca (castra), the Roman fort for the ancient city Napoca.
- Napoca (genus), a group of jumping spiders known only from Israel, named after the ancient city.
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