Methylitaconate Delta-isomerase

In enzymology, a methylitaconate Δ-isomerase (EC 5.3.3.6) is an enzyme that catalyzes the chemical reaction

Methylitaconate Δ-isomerase
Identifiers
EC no.5.3.3.6
CAS no.9059-08-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
methylitaconate 2,3-dimethylmaleate

Hence, this enzyme has one substrate, methylitaconate, and one product, 2,3-dimethylmaleate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is methylitaconate Delta2-Delta3-isomerase. This enzyme is also called methylitaconate isomerase. This enzyme participates in c5-branched dibasic acid metabolism.

References edit

  • Kung HF, Stadtman TC (1971). "Nicotinic acid metabolism. VI. Purification and properties of alpha-methyleneglutarate mutase (B 12-dependent) and methylitaconate isomerase". J. Biol. Chem. 246 (10): 3378–88. PMID 5574401.