Mesembria or Messembria or Mesambria may refer to:
- Mesembria (Pontus), modern Nesebar, an ancient Greek city on the Black Sea coast of Bulgaria
- Mesembria (Zone), the ancient Greek polis of Zone, on the Aegean coast of Western Thrace, Greece, whose archaeological remains were formerly identified as "Mesembria"
- Mesambrie, another ancient Greek settlement on the Aegean coast of Western Thrace (exact location unknown)
- Mesimvria, Evros, a modern Greek village near Mesembria–Zone.
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