Mantle zone
| Germinal centre | |
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| Image labeled in German, but "Mantel-zone" visible near center. |
The mantle zone (or just mantle) of a lymphatic nodule (or lymphatic follicle) is an outer ring of small lymphocytes surrounding a germinal center.[1]
It is also known as the "corona".[2]
It contains transient lymphocytes.[3]
It is the location of the lymphoma in mantle cell lymphoma.
Pathology
Intermediate magnification micrograph of Castleman disease showing the characteristic expansion of the mantle zone. H&E stain.
Mantle zone expansion may be seen in benign, such as Castleman disease, and malignancy, i.e. Mantle cell lymphoma.
External links
- http://erl.pathology.iupui.edu/HISTO/LABE109.HTM
- BU Histology Learning System: 07102loa - "Lymphoid Tissues and Organs: lymph node, cortex and medulla"
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