M150 or M-150 may refer to:
- M150 Penetration Augmented Munition, an explosive device
- M150 ACOG, a telescopic rifle sight used by the United States Army
- M-150 (Michigan highway), a road in the United States
- M-150 (energy drink), an energy drink from Thailand
This disambiguation page lists articles associated with the same title formed as a letter–number combination.
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