List of biotechnology companies
A biotechnology company is a company whose products or services primarily use biotechnology methods for their production, design or delivery. The United Nations Convention on Biological Diversity defines 'biotechnology' as: "Any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use."[1] In other words, biotechology can be defined as the mere application of technical advances in life science to develop commercial products.
Independent biotechnology companies
- The following is a list of the top 25 independent biotechnology companies listed on a stock exchange ranked by Market Capitalization in Q2 of 2012.[2] It additionally details their market capitalization in Q2 of the previous year (2011), from which the change in value over the year can be calculated.
- Note that it does not include biotechnology companies that are now owned by, or part of, larger pharmaceutical groups - such as Genentech (owned by Roche), Genzyme (Sanofi), or MedImmune (AstraZeneca). It should be viewed as an update and complementary to the previous table below.
| Rank 2012 | Company | Country | Market Cap in 2012 (USD billions) | Market Cap in 2011 (USD billions) | % Change over year (Q2-Q2) | Website |
|---|---|---|---|---|---|---|
| 1 | Novo Nordisk | Denmark | 76.92 | 60.09 | 28.0% | novonordisk.com |
| 2 | Amgen | USA | 60.09 | 49.72 | 20.9% | amgen.com |
| 3 | Gilead Sciences | USA | 40.16 | 32.68 | 28.5% | gilead.com |
| 4 | Biogen Idec | USA | 34.26 | 25.6 | 28.5% | biogenidec.com |
| 5 | Teva Pharmaceutical Industries | Israel | 34.23 | 42.96 | -20.3% | tevapharm.com |
| 6 | Baxter International | USA | 32.27 | 33.36 | -3.3% | baxter.com |
| 7 | Celgene | USA | 28.38 | 27.52 | 3.1% | celgene.com |
| 8 | Merck KGaA | Germany | 21.16 | 20.14 | 5.1% | merckgroup.com |
| 9 | CSL | Australia | 21.11 | 18.33 | 15.2% | csl.com.au |
| 10 | Alexion Pharmaceuticals | USA | 18.85 | 10.48 | 79.9% | alxn.com |
| 11 | Vertex Pharmaceuticals | USA | 10.64 | 10.79 | -1.4% | vrtx.com |
| 12 | Regeneron | USA | 11.3 | 5.09 | 122.0% | regeneron.com |
| 13 | Forest Laboratories | USA | 8.87 | 9.09 | -2.4% | frx.com |
| 14 | UCB | Belgium | 8.77 | 6.84 | 28.2% | ucb.com |
| 15 | Élan | Ireland | 8.63 | 6.67 | 29.4% | elan.com |
| 16 | BioMarin Pharmaceutical | USA | 5.35 | 3.32 | 61.1% | biomarinpharm.com |
| 17 | Dr. Reddy's Laboratories | India | 5.35 | 5.03 | 6.4% | drreddys.com |
| 18 | Amylin Pharmaceuticals § | USA | 5.06 | 1.74 | 190.8% | amylin.com |
| 19 | Onyx Pharmaceuticals | USA | 5.06 | 2.1 | 141.0% | onyx.com |
| 20 | Actelion | Switzerland | 4.65 | 5.02 | -7.4% | actelion.com |
| 21 | Warner Chilcott | Ireland | 4.49 | 5.69 | -21.1% | wcrx.com |
| 22 | Ranbaxy Laboratories | India | 3.71 | 4.08 | -9.1% | ranbaxy.com |
| 23 | Medivation | USA | 3.65 | 0.683 | 433.4% | medivation.com |
| 24 | ARIAD Pharmaceuticals | USA | 3.18 | 1.58 | 101.3% | ariad.com |
| 25 | Seattle Genetics | USA | 2.92 | 1.89 | 54.5% | seagen.com |
§ - Acquired by Bristol-Myers Squibb in a $7 billion deal completed Aug 8 2012 (therefore no longer independent in this list going forward).
NOTE: Market Cap is an indication of the perceived value of the company (&/or its technology) and not necessarily a measure of its size, sales or number of employees; it is indicative of both current and future scale and profitability of the company. The year-on-year change in its value is indicative of the (real or perceived) performance or progress of that company over that year.
Biotechnology companies
 |
This article's factual accuracy may be compromised due to out-of-date information. (February 2013) |
- The following is a list of the top 100 companies ranked by revenue (2006).[3] The first nine companies qualify for the list of the top 50 pharmaceutical companies.
Examining the list of the top 100 such companies, below, shows that many have negative income. This is consistent with the notion that only one in ten biotechnology companies were considered profitable in mid-2005.[4]
| Rank 2006 | Company | Country | Revenue in 2006 (USD millions) | R&D in 2006 (USD millions) | Net income/ (loss) in 2006 (USD millions) | Employees in 2006 |
|---|---|---|---|---|---|---|
| 1 | Amgen | USA | 14,268.0 | 3,366.0 | 2,950.0 | 20,100 |
| 2 | Genentech | USA | 11,724.0 | 2,995.0 | 2,740.0 | 10,001+ |
| 3 | Genzyme | USA | 3,187.0 | 650.0 | (16.8) | 9,000+ |
| 4 | UCB | Belgium | 3,169.6 | 772.6 | 461.1 | 8,477 |
| 5 | Gilead Sciences | USA | 3,026.1 | 383.9 | (1,190.0) | 7,575 |
| 6 | Serono | Switzerland | 2,804.9 | 560.5 | 735.4 | 4,775 |
| 7 | Biogen Idec | USA | 2,683.0 | 718.4 | 217.5 | 3,750 |
| 8 | CSL | Australia | 2,148.3 | 119.1 | 86.8 | 2,895 |
| 9 | Cephalon | USA | 1,764.1 | 403.4 | 144.8 | 2,515 |
| 10 | MedImmune | USA | 1,276.8 | 448.9 | 48.7 | 2,359 |
| 11 | Celgene | USA | 898.9 | 258.6 | 69.0 | 1,864 |
| 12 | Abraxis BioScience | USA | 765.5 | 96.9 | (46.9) | 1,734 |
| 13 | Actelion | Switzerland | 754.6 | 169.0 | 192.4 | 1,550 |
| 14 | ImClone Systems | USA | 677.8 | 112.1 | 370.7 | 1,287 |
| 15 | Amylin Pharmaceuticals | USA | 510.9 | 222.1 | (218.9) | 1,100 |
| 16 | Millennium Pharmaceuticals | USA | 486.8 | 318.2 | (44.0) | 1,073 |
| 17 | PDL BioPharma | USA | 414.8 | 260.7 | (130.0) | 993 |
| 18 | OSI Pharmaceuticals | USA | 375.7 | 176.7 | (582.2) | 962 |
| 19 | MGI Pharma | USA | 342.8 | 100.1 | (40.2) | 947 |
| 20 | Pharmion | USA | 238.6 | 70.1 | (91.0) | 793 |
| 21 | Nektar Therapeutics | USA | 217.7 | 149.4 | (154.8) | 770 |
| 22 | Vertex Pharmaceuticals | USA | 216.4 | 371.7 | (206.9) | 760 |
| 23 | Biocon | India | 200.3 | 30.5 | 43.5 | 1,838 |
| 24 | Cubist Pharmaceuticals | USA | 194.7 | 57.4 | (0.4) | 746 |
| 25 | Enzon Pharmaceuticals | USA | 185.7 | 43.5 | 21.3 | 722 |
| 26 | QLT | Canada | 175.1 | 56.4 | (101.6) | 653 |
| 27 | ViroPharma | USA | 167.2 | 19.2 | 66.7 | 651 |
| 28 | Alkermes | USA | 166.6 | 89.1 | 3.8 | 617 |
| 29 | Crucell | Netherlands | 165.3 | 84.9 | (110.0) | 611 |
| 30 | United Therapeutics | USA | 159.6 | 57.6 | 74.0 | 585 |
| 31 | LifeCell | USA | 141.7 | 16.5 | 20.5 | 573 |
| 32 | Ligand Pharmaceuticals | USA | 141.0 | 41.9 | (31.7) | 540 |
| 33 | Myriad Genetics | USA | 114.3 | 83.8 | (38.2) | 511 |
| 34 | Exelixis | USA | 98.7 | 185.5 | (101.5) | 500 |
| 35 | Cangene | Canada | 96.8 | 22.1 | 11.6 | 498 |
| 36 | InterMune | USA | 90.8 | 103.8 | (107.2) | 492 |
| 37 | Nabi Biopharmaceuticals | USA | 89.9 | 37.6 | (58.7) | 487 |
| 38 | BioMarin Pharmaceutical | USA | 84.2 | 66.7 | (28.5) | 417 |
| 39 | Lexicon Pharmaceuticals | USA | 72.8 | 106.7 | (54.3) | 410 |
| 40 | Progenics Pharmaceuticals | USA | 69.9 | 61.7 | (21.6) | 410 |
| 41 | Innogenetics | Belgium | 67.5 | 32.1 | (31.5) | 371 |
| 42 | Idenix Pharmaceuticals | USA | 67.4 | 96.1 | (75.1) | 359 |
| 43 | MorphoSys | Germany | 66.6 | 21.9 | 7.6 | 336 |
| 44 | Omrix Biopharmaceuticals | USA | 63.8 | 3.4 | 23.1 | 335 |
| 45 | Regeneron Pharmaceuticals | USA | 63.4 | 137.1 | (102.3) | 323 |
| 46 | Acambis | UK | 57.0 | 68.2 | (30.4) | 285 |
| 47 | Tanox | USA | 56.1 | 53.4 | (2.6) | 285 |
| 48 | ViaCell | USA | 54.4 | 14.0 | (21.0) | 282 |
| 49 | Indevus Pharmaceuticals | USA | 50.5 | 43.2 | -50.6 | 279 |
| 50 | Medarex | USA | 48.6 | 194.5 | (181.7) | 277 |
| 51 | NPS Pharmaceuticals | USA | 48.5 | 68.4 | (112.7) | 276 |
| 52 | Monogram Biosciences | USA | 48.0 | 19.0 | (38.7) | 274 |
| 53 | Oscient Pharmaceuticals | USA | 46.2 | 12.4 | (78.5) | 267 |
| 54 | Array BioPharma | USA | 45.0 | 33.4 | (39.6) | 263 |
| 55 | AEterna Zentaris | Canada | 41.4 | 28.7 | 33.4 | 260 |
| 56 | IsoTis | Switzerland | 40.7 | 7.7 | (18.5) | 255 |
| 57 | Enzo Biochem | USA | 39.8 | 7.9 | (15.7) | 255 |
| 58 | CuraGen | USA | 39.6 | 58.5 | (59.8) | 254 |
| 59 | Neurocrine Biosciences | USA | 39.2 | 97.7 | (107.2) | 254 |
| 60 | MediGene | Germany | 38.4 | 26.7 | (8.7) | 248 |
| 61 | Life Therapeutics | Australia | 37.6 | 0.1 | (31.2) | 245 |
| 62 | Inspire Pharmaceuticals | USA | 37.1 | 42.5 | (42.1) | 238 |
| 63 | CV Therapeutics | USA | 36.8 | 135.3 | (274.3) | 233 |
| 64 | Cerus | USA | 35.6 | 29.5 | (4.8) | 208 |
| 65 | SciClone Pharmaceuticals | USA | 32.7 | 14.1 | 0.7 | 197 |
| 66 | ImmunoGen | USA | 32.1 | 40.9 | (17.8) | 197 |
| 67 | Protherics | UK | 30.9 | 11.8 | (16.5) | 196 |
| 68 | Arena Pharmaceuticals | USA | 30.6 | 103.4 | (88.3) | 195 |
| 69 | Vernalis | UK | 30.1 | 71.7 | (78.2) | 192 |
| 70 | Bavarian Nordic | Denmark | 29.5 | 19.9 | (27.1) | 191 |
| 71 | Xoma | USA | 29.5 | 52.1 | (51.8) | 189 |
| 72 | GPC Biotech | Germany | 28.5 | 81.3 | (80.4) | 180 |
| 73 | Micromet | USA | 27.6 | 28.3 | 0.0 | 171 |
| 74 | Targacept | USA | 27.5 | 21.8 | (1.2) | 170 |
| 75 | Carrington Laboratories | USA | 27.4 | 5.8 | (7.6) | 166 |
| 76 | Acorda Therapeutics | USA | 27.4 | 12.1 | (60.0) | 158 |
| 77 | Anika Therapeutics | USA | 26.8 | 3.6 | 4.6 | 156 |
| 78 | Human Genome Sciences | USA | 25.8 | 209.2 | (251.2) | 151 |
| 79 | Dusa Pharmaceuticals | USA | 25.6 | 6.2 | (31.3) | 150 |
| 80 | ZymoGenetics | USA | 25.4 | 128.5 | (130.0) | 150 |
| 81 | Maxygen | USA | 25.0 | 49.1 | (16.5) | 147 |
| 82 | Isis Pharmaceuticals | USA | 24.5 | 80.6 | (45.9) | 133 |
| 83 | Genmab | Denmark | 23.9 | 90.6 | (77.4) | 128 |
| 84 | BioSciMed | USA | 23.9 | 11.6 | (1.0) | 126 |
| 85 | Bioniche Life Sciences | Canada | 24.1 | 11.9 | (1.0) | 127 |
| 86 | Vitrolife | Sweden | 23.2 | 3.3 | 2.1 | 124 |
| 87 | Coley Pha | |||||
| 91 | Medivir Group | Sweden | 18.8 | 39.7 | (29.7) | 88 |
| 92 | Peptech | Australia | 18.7 | 4.6 | 3.8 | 85 |
| 93 | Ambrilia Biopharma | Canada | 17.4 | 8.3 | (2.1) | 85 |
| 94 | Cytogen | USA | 17.3 | 7.3 | (15.1) | 85 |
| 95 | Replidyne | USA | 16.0 | 38.3 | (34.6) | 79 |
| 96 | Sinovac Biotech | China | 15.4 | 0.3 | (0.7) | 67 |
| 97 | Trimeris | USA | 15.2 | 18.3 | 7.4 | 64 |
| 98 | Avanir Pharmaceuticals | USA | 15.2 | 29.2 | (62.6) | 64 |
| 99 | Adolor | USA | 15.1 | 56.7 | (69.7) | 51 |
References
- ^ "The Convention on Biological Diversity (Article 2. Use of Terms)." United Nations. 1992. Retrieved on February 6, 2008.
- ^ Top 25 Biotech Companies, Genetic Engineering & Biotechnology News, August 2012
- ^ Top 100 biotechnology companies, MedAdNews, June 2007
- ^ DePalma, Angelo (August 2005), "Twenty-Five Years of Biotech Trends", Genetic Engineering News (Mary Ann Liebert) 25 (14): 1, 14–23, ISSN 1935-472X, retrieved 2008-08-17
External links
- List of Biotech Companies - Biotech Informa
- European Biotechnology Company Guide - European Biotechnology Network
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