Louis Riel. c.1884
- Pierre Bottineau, Minnesota frontiersman, surveyor, diplomat and translator
- Louis Riel, Métis leader who led the Red River Rebellion in 1869 - 1870, the provisional government of Rupert's Land, Manitoba's entry into Confederation in 1870 and later led the North-West Rebellion in 1885.
- Cuthbert Grant, Métis political and military leader
- Gabriel Dumont, Métis military leader during the North-West Rebellion
- Howard Adams, Métis activist, author and leader
- John Norquay, Métis politician, Premier of Manitoba from 1878 to 1887
- Malcolm Norris, Métis politician and activist
- James P. Brady, Métis politician and activist
- Pierre Delorme, Métis politician and activist
- Michel "Mitch" Bouyer, a Métis of French Canadian and Sioux ancestry. He was an interpreter and guide in the Old West. He was a lead scout with the US Seventh Cavalry and died along with Lt.Col. George Armstrong Custer at the Battle of the Little Big Horn on June 25, 1876.
Artists and writers
George R. D. Goulet, 2007 (shown carrying the Métis Flag
) and leading the Grand Entry at the Red River West celebration.
- Sandra Birdsell, daughter of a Métis man and a Russian Mennonite woman, based her award-winning novel Children of the Day in part on her parents' experiences in Manitoba in the 1920s to 1950s.
- Joseph Boyden is an award-winning Canadian author with Irish, Scottish and Métis roots. He won the 2008 Scotiabank Giller Prize for his second novel, Through Black Spruce.
- Robert Boyer (1948–2004) was a Métis Cree artist, best known for his politically charged "Blanket Statements" series of paintings.
- Alec Butler
- George R. D. Goulet is a best-selling Métis author whose books include The Trial of Louis Riel: Justice and Mercy Denied, The Metis: Memorable Events and Memorable Personalities, and The Métis in British Columbia: From Fur Trade Outposts to Colony.
- Dylan Miner, is a Métis printmaker, writer and conceptual artist.
- Ry Moran, a Métis singer/songwriter/composer, is noted for his musical works dealing with Métis history, conflict and cultural rebirth. Ry has been nominated for a number of significant music awards alongside being recognized as a National Aboriginal Youth Role Model in 2008-2009.
- Christine Welsh, a documentary filmmaker and academic.
Politicians, activists, lawyers, physicians and judges
- Rod Bruinooge, a Métis is Member of Parliament for Winnipeg South (Conservative Party of Canada), he was the Parliamentary Secretary to the Minister of Indian Affairs & Northern Development and the Federal Interlocutor for Métis and Non-Status Indians from 2005 until the fall of 2008.
- Todd Ducharme, a Métis, was appointed as a judge in 2004 of the Ontario Supreme Court of Justice.
- Shelly Glover, a Métis is Member of Parliament for Saint-Boniface (Conservative Party of Canada). She is Parliamentary Secretary for Official Languages.
- Rabble.ca editor and Canadian anti-war movement leader Derrick O'Keefe is of partial Métis ancestry, and has Métis membership.
- Former British Columbia New Democratic Party Leader Carole James is of partial Métis ancestry.
- Former Canadian Prime Minister Paul Martin is of Métis ancestry through his maternal line.
- Colleen Klein, wife of former Alberta Premier Ralph Klein, is of Métis ancestry.
- Pierre Leon Muise, Acadian and Métis, was appointed a Nova Scotia provincial judge in 2009.
Three Winnipeg Metis brothers: Dr. Conrad Hoy, Dr. Murray Hoy and Dr. Gerald Hoy descendents of the original Red River Settlers.
- Architect Douglas Cardinal is of Métis and Blackfoot ancestry.
- Actress Tantoo Cardinal is of Métis and Cree ancestry
- Jon Gallant is bassist for the Canadian band Billy Talent.
- Hypnotist Scott Ward is of Ojibway / Métis ancestry.
- Actor Dakota House is of Cree / Métis ancestry.
- City of Castlegar BC Fire Chief Gerry Rempel is of Métis ancestry