James Sanderson may refer to:
- James Sanderson (musician) (1769–c. 1841), English violinist and composer
- James Sanderson (naval officer) (1926–2010), U.S. Navy admiral
- Sir James Sanderson, 1st Baronet (1741–1798), British banker and politician
- James Sanderson (swimmer) (born 1993), Gibraltarian swimmer
- James Sanderson (rugby union) (1852–1930), Scottish rugby union player
- James Sanderson (military surgeon) (1812–1891), military surgeon in India and amateur meteorologist
- James Sanderson (curler), Scottish curler
This disambiguation page lists articles about people with the same name.
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