Centromere protein R is a protein that in humans is encoded by the ITGB3BP gene.[5][6][7]

ITGB3BP
Identifiers
AliasesITGB3BP, CENP-R, CENPR, HSU37139, NRIF3, TAP20, integrin subunit beta 3 binding protein
External IDsOMIM: 605494 MGI: 1914983 HomoloGene: 8617 GeneCards: ITGB3BP
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001206739
NM_014288
NM_001347145
NM_001347147
NM_001347148

NM_026348
NM_001362974
NM_001362975
NM_001362976

RefSeq (protein)

NP_001193668
NP_001334074
NP_001334076
NP_001334077
NP_055103

NP_080624
NP_001349903
NP_001349904
NP_001349905

Location (UCSC)Chr 1: 63.44 – 63.59 MbChr 4: 99.65 – 99.79 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions edit

ITGB3BP has been shown to interact with:

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000142856Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028549Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Shattil SJ, O'Toole T, Eigenthaler M, Thon V, Williams M, Babior BM, Ginsberg MH (December 1995). "Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit". J Cell Biol. 131 (3): 807–16. doi:10.1083/jcb.131.3.807. PMC 2120613. PMID 7593198.
  6. ^ a b c Li D, Desai-Yajnik V, Lo E, Schapira M, Abagyan R, Samuels HH (February 2000). "NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors". Mol Cell Biol. 19 (10): 7191–202. doi:10.1128/mcb.19.10.7191. PMC 84712. PMID 10490654.
  7. ^ "Entrez Gene: ITGB3BP integrin beta 3 binding protein (beta3-endonexin)".
  8. ^ Fujimoto TT, Katsutani S, Shimomura T, Fujimura K (January 2002). "Novel alternatively spliced form of beta(3)-endonexin". Thromb. Res. 105 (1): 63–70. doi:10.1016/s0049-3848(01)00405-4. PMID 11864709.
  9. ^ Ohtoshi A, Maeda T, Higashi H, Ashizawa S, Yamada M, Hatakeyama M (January 2000). "beta3-endonexin as a novel inhibitor of cyclin A-associated kinase". Biochem. Biophys. Res. Commun. 267 (3): 947–52. doi:10.1006/bbrc.1999.2007. PMID 10673397.
  10. ^ Besta F, Massberg S, Brand K, Müller E, Page S, Grüner S, Lorenz M, Sadoul K, Kolanus W, Lengyel E, Gawaz M (October 2002). "Role of beta(3)-endonexin in the regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor". J. Cell Sci. 115 (Pt 20): 3879–88. doi:10.1242/jcs.00081. PMID 12244126.
  11. ^ a b Li D, Wang F, Samuels HH (December 2001). "Domain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation". Mol. Cell. Biol. 21 (24): 8371–84. doi:10.1128/MCB.21.24.8371-8384.2001. PMC 100002. PMID 11713274.

Further reading edit