Xanthomycin A

(Redirected from Guamecycline)

Xanthomycin A is an antibiotic with in vitro antitumor activity isolated from Streptomyces.[1]

Xanthomycin A
Names
Other names
Guamecycline; Tetrabiguanide
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.036.904 Edit this at Wikidata
UNII
  • InChI=1S/C29H38N8O8/c1-28(44)13-5-4-6-16(38)17(13)21(39)18-14(28)11-15-20(35(2)3)22(40)19(24(42)29(15,45)23(18)41)25(43)33-12-36-7-9-37(10-8-36)27(32)34-26(30)31/h4-6,14-15,20,38-39,42,44-45H,7-12H2,1-3H3,(H,33,43)(H5,30,31,32,34)/t14-,15-,20-,28+,29-/m0/s1 checkY
    Key: FAMUIRDLAWWMCQ-AQFAATAFSA-N checkY
  • C[C@]1(c2cccc(c2C(=C3[C@@H]1C[C@H]4[C@@H](C(=O)C(=C([C@]4(C3=O)O)O)C(=O)NCN5CCN(CC5)C(=N)N=C(N)N)N(C)C)O)O)O
Properties
C29H38N8O8
Molar mass 626.671 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References

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  1. ^ Nishimura T, Kitajima J, Omura S, Tanaka N (1981). "Antitumor activity of an antibiotic identical with or closely related to xanthomycin A". J Antibiot. 34 (7): 856–861. doi:10.7164/antibiotics.34.856. PMID 7287588.{{cite journal}}: CS1 maint: multiple names: authors list (link)