Frontonasal prominence
| Frontonasal prominence | |
|---|---|
 |
|
| Under surface of the head of a human embryo about twenty-nine days old. (Frontonasal process labeled at center left.) | |
| Latin | prominentia frontonasalis |
| Gray's | subject #13 67 |
| Code | TE E5.3.0.0.0.0.6 |
During the third week of embryonic development, two areas of thickened ectoderm, the olfactory areas, appear immediately under the fore-brain in the anterior wall of the stomodeum, one on either side of a region termed the frontonasal prominence (or process).
By the upgrowth of the surrounding parts these areas are converted into pits, the olfactory pits, which indent the frontonasal prominence and divide it into a medial and two lateral nasal processes.
There is some evidence that development involves Sonic hedgehog and Fibroblast growth factor 8.[1]
References
- ^ Abzhanov A, Cordero DR, Sen J, Tabin CJ, Helms JA (December 2007). "Cross-regulatory interactions between Fgf8 and Shh in the avian frontonasal prominence". Congenit Anom (Kyoto) 47 (4): 136–48. doi:10.1111/j.1741-4520.2007.00162.x. PMID 17988255.
External links
- hednk-027 — Embryo Images at University of North Carolina
- Flash animation at indiana.edu
- ent/30 at eMedicine
This article incorporates text from a public domain edition of Gray's Anatomy.
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