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Summary
| Description |
English: When two procaspase-8 are recruited to the DISC, their caspase domains undergo conformational changes with the consequent liberation of P12 subunit which is processed to the small P10 catalytic subunit. The intermediate capspase-8 breaks in the region between DED and P18 subunit. The two molecules of the two caspase-8 intermediates associate with the two P10 subunits to form the active protease. |
| Date | |
| Source | processing of procaspase-8 |
| Author | Aina Estany |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 15:31, 20 October 2016 | | 1,820 × 802 (141 KB) | BQUB16-Aestany | User created page with UploadWizard |
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