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Summary
| Description |
English: Flock house virus genome organization and functional map of replicase protein A.
(A) The bipartite FHV RNA genome encodes the viral replicase protein A on RNA1 and the capsid protein precursor on RNA2. Protein A mediates synthesis of a negative strand copy of the genomic RNAs which serves as template for synthesis of progeny positive strand RNAs, and an additional partial negative strand copy of RNA1 to template a 3’ co-terminal subgenomic RNA3. RNA3 potentially encodes protein B1, co-terminal with the C-terminus of protein A, and protein B2 which has anti-RNAi function. (B) A linear representation of protein A annotated to show membrane-association and enzymatic domains, and several regions independently capable of homotypic multimerization. |
| Date | |
| Source |
eLife 2017;6:e25940 DOI: 10.7554/eLife.25940 https://elifesciences.org/articles/25940 |
| Author | Kenneth J Ertel, Desirée Benefield, Daniel Castaño-Diez, Janice G Pennington, Mark Horswill, Johan A den Boon, Marisa S Otegui, and Paul Ahlquist |
| Other versions |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 10:13, 2 December 2020 | | 2,413 × 1,626 (270 KB) | Guest2625 | Uploaded a work by Kenneth J Ertel, Desirée Benefield, Daniel Castaño-Diez, Janice G Pennington, Mark Horswill, Johan A den Boon, Marisa S Otegui, and Paul Ahlquist from eLife 2017;6:e25940 DOI: 10.7554/eLife.25940 https://elifesciences.org/articles/25940 with UploadWizard |
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