Fenquizone

Fenquizone
Clinical data
ATC code	C03BA13 (WHO) ;
Identifiers
	IUPAC name 7-chloro-4-oxo-2-phenyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide;
CAS Number	20287-37-0;
PubChem CID	68548;
ChemSpider	61822 ;
UNII	LJ1U13R8IK;
KEGG	D04161 ;
ECHA InfoCard	100.039.702
Chemical and physical data
Formula	C14H12ClN3O3S
Molar mass	337.78 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=S(=O)(c3c(Cl)cc2c(C(=O)NC(c1ccccc1)N2)c3)N;
	InChI InChI=1S/C14H12ClN3O3S/c15-10-7-11-9(6-12(10)22(16,20)21)14(19)18-13(17-11)8-4-2-1-3-5-8/h1-7,13,17H,(H,18,19)(H2,16,20,21) ; Key:DBDTUXMDTSTPQZ-UHFFFAOYSA-N ;
	(verify)

Fenquizone (INN) is a diuretic, part of the class of low-ceiling sulfonamide diuretics.^[1] Fenquizone is used primarily in the treatment of oedema and hypertension.^[2]

References edit

^ Ferrando C, Foy JM, Pratt CN, Purvis JR (April 1981). "On the pharmacological actions of a diuretic, fenquizone, with particular reference to its site of action". The Journal of Pharmacy and Pharmacology. 33 (4): 219–22. doi:10.1111/j.2042-7158.1981.tb13761.x. PMID 6115903.
^ "Fenquizone". Drug Information from MIMS. Thailand.^{[permanent dead link]}

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[pmid6115903-1] Ferrando C, Foy JM, Pratt CN, Purvis JR (April 1981). "On the pharmacological actions of a diuretic, fenquizone, with particular reference to its site of action". The Journal of Pharmacy and Pharmacology. 33 (4): 219–22. doi:10.1111/j.2042-7158.1981.tb13761.x. PMID 6115903.

[2] "Fenquizone". Drug Information from MIMS. Thailand.^{[permanent dead link]}

[1]

[2]

Clinical data

ATC code	C03BA13 (WHO)
Identifiers
IUPAC name 7-chloro-4-oxo-2-phenyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
CAS Number	20287-37-0
PubChem CID	68548
ChemSpider	61822^Y
UNII	LJ1U13R8IK
KEGG	D04161^Y
ECHA InfoCard	100.039.702
Chemical and physical data
Formula	C₁₄H₁₂ClN₃O₃S
Molar mass	337.78 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=S(=O)(c3c(Cl)cc2c(C(=O)NC(c1ccccc1)N2)c3)N
InChI InChI=1S/C14H12ClN3O3S/c15-10-7-11-9(6-12(10)22(16,20)21)14(19)18-13(17-11)8-4-2-1-3-5-8/h1-7,13,17H,(H,18,19)(H2,16,20,21)^Y Key:DBDTUXMDTSTPQZ-UHFFFAOYSA-N^Y
(verify)

Fenquizone

See also edit

References edit