Translation initiation factor eIF-2B subunit alpha is a protein that in humans is encoded by the EIF2B1 gene.[5]

EIF2B1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesEIF2B1, EIF2B, EIF2BA, eukaryotic translation initiation factor 2B subunit alpha, EIF2Balpha
External IDsOMIM: 606686 MGI: 2384802 HomoloGene: 1080 GeneCards: EIF2B1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001414

NM_145371

RefSeq (protein)

NP_001405

NP_663346

Location (UCSC)Chr 12: 123.62 – 123.63 MbChr 5: 124.71 – 124.72 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions edit

EIF2B1 has been shown to interact with EIF2B5.[6][7]

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000111361 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029388 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa".
  6. ^ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  7. ^ Anthony TG, Fabian JR, Kimball SR, Jefferson LS (June 2000). "Identification of domains within the epsilon-subunit of the translation initiation factor eIF2B that are necessary for guanine nucleotide exchange activity and eIF2B holoprotein formation". Biochim. Biophys. Acta. 1492 (1): 56–62. doi:10.1016/S0167-4781(00)00062-2. PMID 10858531.

Further reading edit