Doomsday Machine may refer to:
- Doomsday device, a hypothetical weapon which could destroy all life on the Earth
- Doomsday Machine (film), a 1972 science-fiction film
- The Doomsday Machine (book), a 2012 non-fiction book arguing that nuclear energy is a kind of 'Doomsday' strategy
- "The Doomsday Machine" (Star Trek: The Original Series), a 1967 episode of Star Trek: The Original Series
- Doomsday Machine (album), a 2005 album by melodic death metal band Arch Enemy
- Doomsday Machine, a fictional army from the board game Neuroshima Hex!
- The Doomsday Machine: Confessions of a Nuclear War Planner (2017), book by Daniel Ellsberg
This disambiguation page lists articles associated with the title Doomsday Machine.
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