Delphinium denudatum

      Delphinium denudatum
      Scientific classification
      Kingdom: Plantae
      Division: Magnoliophyta
      Class: Magnoliopsida
      Order: Ranunculales
      Family: Ranunculaceae
      Genus: Delphinium
      Species: D. denudatum
      Binomial name
      Delphinium denudatum
      Wall

      Delphinium denudatum is a species of the genus Delphinium.

      Habitat

      Delphinium denudatum is found on the outer ranges of western Himalayas from Kashmir to Kumaon at a height between 8000 to 12000 feet above sea level.

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      Medicinal properties

      It is one of the important drugs used as indigenous medicine in India, especially in Unani medicine.[1][2] Its vernacular name is Jadwar.

      The roots of the plant are reported to be useful in a variety of ailments such as aconite poisoning, brain diseases, fungal infection, piles and toothache as analgesic and astringent.[3][4][5] A number of studies have been done on its phytochemical and pharmacological properties.[6][7]

      Its use in opium addiction is mentioned in some classical literature,[8][9] which has been verified and validated in morphine-induced physical dependent de-addiction studies.[10][11][12][13][14][15][16][17][18][19]

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      References

      1. ^ Qudsia Nizami & MA Jafri. Unani drug, Jadwar (Delphinium denudatum Wall.) - A review. Indian Journal of Traditional Knowledge 2006; 5 (4): 463-467
      2. ^ Zafar S, Aftab MA, Siddiqui TA. Jadwar (Delphinium denudatum Wall.) Roots – A Boon in Unani Medicine, Hamdard Medicus, Vol. XLVI, No. 2, 2003: 9-14
      3. ^ Baytar Ibn. Jame al Mufradat al advia wal aghzia. Cairo: Bulak Press; 1874: 159
      4. ^ Khory RN, Katrak NN. Materia Medica of India and their therapeutics. Delhi: Neeraj Publishing House; 1985: 10–11
      5. ^ Rahman A, Nasreen A, Akhtar F, Shekhani MS, Clardy J, Parvez M, Choudhary MI. Antifungal diterpenoid alkaloids from Delphinium denudatum. J Nat Prod. 1997;60:472–4
      6. ^ Singh N, Singh A, Malik MS. Delphinium denudatum alkaloid, the structure of denudatine. Chem Ind. 1961: 1909-11
      7. ^ Singh N, Chopra KL. Diterpine alkaloid isolation and study of two new alkaloids. J Pharma and Pharmaceutic. 1962;14:288–93
      8. ^ Khan Najmul Ghani. Qarabadin-i Najmul Ghani (Urdu). 2nd ed. Lucknow: Naval Kishore Press; 1928: 621
      9. ^ Shirazi IM. Treatise on Opium. A 16th Century Persian manuscript Aligarh: Zillur Rahman Library, Ibn Sina Academy of Medieval Medicine & Sciences; Scribed between 1737 and 1744. p. 28.
      10. ^ Rahman, SZ (Syed Ziaur Rahman); Khan, RA; Kumar, A (May 2002). "Experimental study of the morphine de-addiction properties of Delphinium denudatum Wall.". BMC Complement Altern Med 2 (6). doi:10.1186/1472-6882-2-6. PMID 12036433. 
      11. ^ Chase, Christina (June 2003). "Study shows Delphinium denudatum aids in de-addiction of morphine (Review)". HerbClip, American Botanical Council, Austin, TX, USA: HC#010133–234. 
      12. ^ Rahman, SZ; Khan, RA; Kumar, A (December 2003). "CNS depressant effect of delphinium denudatum wall. with special reference to its role in morphine addiction". Journal of Neurochemistry 87 (Suppl. 1): 68–68.  Text " IDS Number: 753PR " ignored (help); Unknown parameter |unused_data= ignored (help)
      13. ^ Rahman, SZ; Khan, RA; Kumar, A (February 2004). "Delphinium denudatum Wall and its CNS activities particularly in morphine addiction". Journal of Neurochemistry 88 (Suppl. 1): 34–34.  Text " IDS Number: 775UH " ignored (help); Unknown parameter |unused_data= ignored (help)
      14. ^ Rahman, SZ; Khan, RA; Kumar, A (August 2004). "Delphinium denudatum Wall and its CNS depressant effect particularly in morphine addiction". Journal of Neurochemistry 90 (Suppl. 1): 145–145.  Text " IDS Number: 852NB " ignored (help); Unknown parameter |unused_data= ignored (help)
      15. ^ Rahman, SZ; Khan, RA; Kumar, A (August 2005). "Pharmacological studies of an indigenous CNS-active drug delphinium denudatum wall. in view of its role in morphine addiction". Journal of Neurochemistry 94 (Suppl. 2): 95–95.  Text " IDS Number: 961PD " ignored (help); Unknown parameter |unused_data= ignored (help)
      16. ^ Rahman, SZ; Khan, RA; Kumar, A (August 2007). "Pharmacological study of delphinium denudatum wall. in morphine de-addiction.". Journal of Neurochemistry 102 (Suppl. 1): 142–143.  Text " IDS Number: 203RL " ignored (help); Unknown parameter |unused_data= ignored (help)
      17. ^ Rahman, S. Z., Khan R. A. & Kumar A. A Study of Delphinium denudatum Wall. in morphine dependence. In: Khan SS, editor. Vistas in Ethnobotany, Ind J Applied Pure Biol. Vol. 1. 2000: 111–125
      18. ^ Rahman, S. Z., Khan R.A & Kumar A. Preclinical study of delphinium denudatum wall. in morphine de-addiction. Journal of Pharmacological and Toxicological Methods September–October 2007, Volume 56 (2): e4
      19. ^ Rahman, S. Z., Khan, R. A & Kumar, A. A Study of Delphinium denudatum in moderately induced morphine dependence, Proceedings, 6th Internet World Congress for Biomedical Sciences, Castilla La Mancha University, Spain, February 14–25, 2000
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      Last modified on 9 May 2013, at 03:07