AE2 may refer to:
- HMAS AE2, E-class submarine of the Royal Australian Navy
- Aero Ae 02, a design of Czechoslovakian plane
- Anion Exchanger 2, transport protein
- Ape Escape 2
- A size designation for Constantinian bronze coins
- Applied Energistics 2, a popular mod for the video game Minecraft
- Aminoestradiol, a synthetic estrogen
This disambiguation page lists articles associated with the same title formed as a letter–number combination.
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